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. 2022 Sep 14;12:15469. doi: 10.1038/s41598-022-19847-5

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© The Author(s) 2022, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Transcriptomic data (relative gene expression levels) for CD16++ blood monocytes of late-onset PE (loPE) and control groups. Volcano plot (a) provides a comparative overview of gene expression of CD16++ monocytes of loPE (n = 6) vs control group (n = 6). Each point in the plot corresponds to a gene. The red- and green-colored genes positioned above the horizontal dotted line are significantly (p < 0.05) up- or down-regulated in loPE CD14++ cells, respectively. The data were analyzed with TAC Software 4.0.2 using Affymetrix default analysis settings and RMA algorithm. Enrichment analysis for upregulated genes (b) and downregulated genes (c) grouped in the PANTHER ontology by molecular pathway and listed in order starting from the most represented.