Table 3.

Reproductive Factors Associated with Intestinal-Type Gastric Cancer Risk in Multivariate Analysis

Factor	Odds ratio (95% CI)	p-value
Total females
Age at diagnosis of gastric cancer	1.066 (1.042–1.091)	<0.001*
Age at menarche	0.974 (0.694–1.366)	0.877
Fertility years	0.962 (0.702–1.313)	0.799
Parity ≥3 (vs nulliparity or parity <3)	1.700 (1.055–2.878)	0.048*
Breast feeding ≥6 mo (no or <6 mo)	1.131 (0.665–1.924)	0.651
Menopause (vs premenopausal status)	0.538 (0.252–1.147)	0.109
Postmenopausal females
Age at diagnosis of gastric cancer	1.075 (1.039-1.113)	<0.001
Age at menarche	1.073 (0.914–1.260)	0.833
Parity ≥3 (vs nulliparity or parity <3)	1.775 (1.012–3.114)	0.045*
Breast feeding ≥6 mo (no or <6 mo)	1.144 (0.614–2.134)	0.672
≥20 yr after menopause (vs <20 yr after menopause)	0.908 (0.352–2.340)	0.841
Premenopausal females
Age at diagnosis	0.893 (0.694–1.148)	0.378
Fertility years	1.147 (1.043–1.261)	0.005*
Parity ≥2	2.577 (0.783–8.486)	0.119

CI, confidence interval.

*Statistically significant, p<0.05.