Table 6.
Logistic Regression Analysis for Adverse Drug Events
| Variable | Univariable analysis | |
|---|---|---|
| OR (95% CI) | p-value | |
| Sex (female/male) | 1.333 (0.552–3.223) | 0.523 |
| Age | 1.013 (0.987–1.040) | 0.333 |
| Age at diagnosis | 1.014 (0.986–1.041) | 0.331 |
| Disease duration | 1.007 (0.935–1.084) | 0.859 |
| Prior biologics use | 0.446 (0.096–2.079) | 0.304 |
| Concomitant steroid | 1.553 (0.651–3.706) | 0.321 |
| Concomitant immunomodulator | 1.116 (0.479–2.602) | 0.780 |
| Partial Mayo score at baseline | 0.801 (0.592–1.083) | 0.150 |
| Full Mayo score at baseline | 0.800 (0.559–1.146) | 0.224 |
| Mayo endoscopy score at baseline (severe/moderate)* | 1.980 (0.674–5.813) | 0.214 |
OR, odds ratio; CI, confidence interval.
*Due to the small number of subjects who had a mild Mayo endoscopy score at baseline, these subjects were excluded from the logistic regression; variables with p-values <0.2 in univariable analysis were used for multivariate analysis.