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. 2022 Sep 14;12:15435. doi: 10.1038/s41598-022-19409-9

Table 2.

Bivariate and multivariate comparisons of total vitamin D levels according to adiposity categories, overall and stratified by sex, CoLaus|PsyCoLaus study, Lausanne.

N Overall Women Men
Bivariate Multivariate N Bivariate Multivariate N Bivariate Multivariate
Body mass index
Underweight 102 56.5 ± 29.9 52.6 ± 1.9 81 59.4 ± 30.1 55.9 ± 2.2 21 45.3 ± 26.8 42.4 ± 3.9
Normal 3012 50.2 ± 23.3 49.5 ± 0.4 1869 51.4 ± 23.2 51.0 ± 0.5 1143 48.1 ± 23.4 47.3 ± 0.5
Overweight 2377 46.3 ± 21.5 46.6 ± 0.4 963 46.1 ± 20.5 46.1 ± 0.6 1414 46.4 ± 22.2 46.8 ± 0.5
Obesity 994 40.6 ± 20.3 42.1 ± 0.6 488 39.6 ± 19.7 41.8 ± 0.9 506 41.4 ± 20.9 42.2 ± 0.8
p-value  < 0.001  < 0.001*  < 0.001  < 0.001*  < 0.001 0.945*
Abdominal obesity
Normal 4572 49.1 ± 23.0 49.0 ± 0.3 2286 50.7 ± 23.1 50.5 ± 0.4 2286 47.5 ± 22.9 47.3 ± 0.4
Obesity 1913 43.3 ± 21.1 43.5 ± 0.4 1115 43.8 ± 20.9 44.2 ± 0.6 798 42.5 ± 21.3 43.2 ± 0.7
p-value  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001
Waist to height ratio
Normal 2487 51 ± 23.9 50.4 ± 0.4 1715 51.7 ± 23.5 51.3 ± 0.5 772 49.5 ± 24.7 48.5 ± 0.7
Obesity 3998 45.1 ± 21.5 45.5 ± 0.3 1686 45.1 ± 21.1 45.5 ± 0.5 2312 45.1 ± 21.7 45.4 ± 0.4
p-value  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001
Conicity index
Normal 2501 49.8 ± 23.2 49.6 ± 0.4 1538 50.2 ± 22.7 50.1 ± 0.5 963 49.3 ± 23.9 48.9 ± 0.6
Elevated 3984 45.8 ± 22.1 46.0 ± 0.3 1863 47.0 ± 22.4 47.0 ± 0.5 2121 44.8 ± 21.8 45.0 ± 0.4
p-value  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001  < 0.001
BRI quartiles
First 1625 51.6 ± 24.1 51.0 ± 0.5 854 53.1 ± 23.9 52.7 ± 0.7 772 49.5 ± 24.7 48.8 ± 0.7
Second 1622 49.3 ± 22.8 49.2 ± 0.5 861 50.3 ± 23.1 50.3 ± 0.7 772 47.6 ± 22.0 47.6 ± 0.7
Third 1622 46.6 ± 21.4 46.1 ± 0.5 836 47.7 ± 21.1 47.5 ± 0.7 773 45.4 ± 21.5 45.0 ± 0.7
Fourth 1616 42.1 ± 21.0 43.1 ± 0.5 850 42.5 ± 20.9 43.1 ± 0.7 767 42.4 ± 21.4 43.4 ± 0.7
p-value  < 0.001  < 0.001*  < 0.001  < 0.001*  < 0.001  < 0.001*
ABSI quartiles
First 1622 48.8 ± 22.4 48.6 ± 0.5 851 48.7 ± 22.2 49.0 ± 0.7 771 49.2 ± 23.7 49.4 ± 0.7
Second 1621 48.2 ± 22.7 48.2 ± 0.5 850 47.8 ± 21.8 47.7 ± 0.7 771 47.1 ± 21.8 46.6 ± 0.7
Third 1621 47.5 ± 22.8 47.4 ± 0.5 850 48.9 ± 23.5 49.3 ± 0.7 771 45.0 ± 22.3 45.4 ± 0.7
Fourth 1621 45.0 ± 22.4 45.3 ± 0.5 850 48.3 ± 23.0 47.6 ± 0.7 771 43.6 ± 22.1 43.6 ± 0.7
p-value  < 0.001  < 0.001* 0.805 0.426*  < 0.001  < 0.001*

*p-value for linear trend. BRI, body roundness index; ABSI, a body shape index. Results are expressed in nmol/L of vitamin D and as mean standard ± deviation for bivariate analyses or as adjusted mean ± standard error for multivariate analyses. Statistical analysis using ANOVA. Multivariate analysis adjusting for age (continuous), nationality (Swiss, other), month, smoking categories (never, former, current), vitamin D supplementation (yes, no) and physical activity (yes, no); for the overall analysis, adjustment on sex (men, women) was also performed.