Table 2.

Probability of bleed_GI occurrence across dose levels of interest based on univariable model

Predicted Cavg,SD	Probability (95% CI)
600 mg Q2W
Geometric mean: 89 μg/mL	0.103 (0.074–0.137)
1200 mg Q2W
Geometric mean: 178 μg/mL	0.151 (0.128–0.177)
1200 mg Q3W
Geometric mean: 136 μg/mL	0.126 (0.101–0.155)
2400 mg Q3W
Geometric mean: 273 μg/mL	0.222 (0.174–0.281)

Bleed_GI gastrointestinal (GI) bleeding event of any grade, C_avg,SD time-averaged concentration over the dosing interval after a single dose, Q2W every 2 weeks, Q3W every 3 weeks