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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Mol Carcinog. 2022 Jul 20;61(10):941–957. doi: 10.1002/mc.23452

Fig 6. Effect of RB and FRB-intake on colon and plasma metabolite profiles during AOM/DSS-induced colon tumorigenesis in germ-free micegf.

Fig 6.

Fig 6.

(A) Principal components analysis of colon (proximal and distal) and plasma metabolite profiles. Relative abundance of metabolites (B) in proximal colon tissue; (C) in distal colon tissue, and (D) in systemic circulation-plasma. Differential metabolite abundance is reported relative to values obtained in control diet fed AOM/DSS treated micegf. Quantified data is represented as Columns (relative fold change); *P ≤ 0.05. RB, rice bran; FRB, Bifidobacterium longum-fermented RB; AOM, azoxymethane; DSS, dextran sodium sulfate; micegf, germ free mice.