Fig. 3.

Validation of the topical detector TAC extrapolation method, assuming 15 min gap between the end of the TAC and the extrapolation time point. A Bland–Altman plot of extrapolated ($\widehat{D}$) and ground truth measurements. B Box plot of differences between extrapolated and ground truth measurements, with central line indicating the median, box bottom and top edges representing the 25th and 75th percentiles, respectively, whiskers indicating the extremes, and red crosses indicating outliers. C, D Representative fits for cases with (C) minimal count rate bias and (D) outlier count rate bias due to a baseline shift after the assumed TAC end time, with automated fit start time indicated by “x” marks in both cases