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. 2022 Sep 14;12:15476. doi: 10.1038/s41598-022-19335-w

Table 1.

Patient characteristics based on aortic valve morphology.

Tricuspid Bicuspid Unicuspid P value
N Number 20 15 15
Age; mean ± standard deviation 62.6 ± 12.9 46.4 ± 15.5 35.8 ± 15.5 < 0.0001*
Sex; % male 80.0 86.7 73.3 0.41
Aortic valve pathology; n (%)
Stenosis 5 (25) 0 (0) 2 (13.3) 0.67
Insufficiency 5 (25) 14 (93.3) 3 (20) 0.002*
Combined 10 (50) 1 (6.7) 10 (66.7) 0.003*
Co-morbidities; n (%)
Hypertension 10 (50) 5 (33.3) 3 (20) 0.02*
Hyperlipidemia 3 (15) 2 (10) 3 (20) 0.62
Medications; n (%)
ß-Blocker 8 (40) 6 (40) 7 (46.7) 0.42
ACE-inhibitor 6 (30) 7 (46.7) 4 (26.7) 0.19
AT1-receptor antagonist 2 (10) 4 (26.7) 4 (26.7) 0.55
Diuretic 7 (35) 5 (33.3) 2 (10) 0.04*
Calcium channel blocker 3 (15) 1 (6.6) 0 (0) 0.08
Statin 7 (35) 4 (26.7) 3 (20) 0.31
Aldosterone antagonist 2 (10) 0 (0) 0 (0) 0.22

*Statistical significance.