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. 2022 Sep 14;12:15468. doi: 10.1038/s41598-022-19684-6

Table 3.

Association between CVH score and tertiles of TPE.

Overall CVH score Models n TPE
T1 T2 T3 AIC p-trend
(B, 95% CI) p value (B, 95% CI) p value
All participants Model 1 1151 0.21 (− 0.02; 0.43) 0.070 0.25 (0.12; 0.38) < 0.001 3336.26 0.031
Model 2 1144 Reference 0.17 (− 0.06; 0.40) 0.140 0.19 (0.14; 0.25) < 0.001 3230.34 0.028
Model 3 1050 0.11 (− 0.12; 0.34) 0.329 0.13 (0.10; 0.15) < 0.001 2953.36 0.003
Boys Model 1 607 0.15 (− 0.03; 0.32) 0.095 0.20 (0.12; 0.29) < 0.001 1813.87 < 0.001
Model 2 604 Reference 0.13 (− 0.08; 0.34) 0.232 0.18 (0.17; 0.19) < 0.001 1765.86 < 0.001
Model 3 551 0.08 (− 0.14; 0.31) 0.452 0.13 (0.12; 0.14) < 0.001 1600.82 < 0.001
Girls Model 1 544 0.09 (− 0.17; 0.35) 0.506 0.12 (− 0.08; 0.32) 0.235 1523.74 0.235
Model 2 540 Reference 0.14 (− 0.07; 0.35) 0.182 0.12 (− 0.07; 0.30) 0.210 1461.21 0.210
Model 3 499 0.12 (− 0.04; 0.27) 0.134 0.09 (− 0.07; 0.25) 0.261 1359.07 0.261

Multilevel mixed-effect linear regression models were used to evaluate the relationship between tertiles of TPE and overall CVH score (continuous). Model 1: adjusted by gender (also interaction). Model 2: adjusted as in model 1 plus age, Tanner stage, fasting, and triglycerides. Model 3: adjusted as in model 2 plus parental education and household income. Municipalities and schools were included as a random effect. p value T3 vs. T1 of TPE, and p-trend of tertiles of TPE < 0.05 are statistically significant.

AIC, Akaike information criteria; B, non-standardized coefficient; CI, confidence interval; CVH, cardiovascular health; TPE, total polyphenol excretion expressed as mg gallic acid equivalent (GAE)/g creatinine; T1, first tertile of TPE (< 85.8 mg GAE/g creatinine); T2, second tertile of TPE (85.8–140.5 mg GAE/g creatinine); T3, third tertile of TPE (> 140.5 mg GAE/g creatinine).