Table 1.
Baseline patient characteristics by Mg level
| Characteristics | Normal serum Mg (n=63) | Hypomagnesemia (n=46) | Total (n=109) | P-value |
|---|---|---|---|---|
| Age (yr) | 69.0 (60.5–76.0) | 68.0 (60.0–76.0) | 69.0 (60.0–76.0) | 0.570 |
| Female | 26 (41.3) | 17 (37.0) | 43 (39.4) | 0.797 |
| BMI (kg/m2) | 22.0 (19.4–24.9) | 20.5 (17.2–23.1) | 21.0 (18.8–23.7) | 0.068 |
| Mg (mg/dl) | 1.9 (1.8–2.0) | 1.5 (1.4–1.6) | 19 (17.4) | < 0.001 |
| Alcohol history | 11 (17.5) | 8 (17.4) | 1.000 | |
| Smoking | 0.118 | |||
| Unknown | 5 (7.9) | 10 (21.7) | 15 (13.8) | |
| Never | 32 (50.8) | 20 (43.5) | 52 (47.7) | |
| Ever | 26 (41.3) | 16 (34.8) | 42 (38.5) | |
| Comorbidity | ||||
| DM | 29 (46.0) | 22 (47.8) | 51 (46.8) | 1.000 |
| Chronic liver disease | 12 (19.0) | 7 (15.2) | 19 (17.4) | 0.791 |
| Chronic kidney disease | 21 (33.3) | 9 (19.6) | 30 (27.5) | 0.170 |
| Cardiovascular disease | 21 (33.3) | 11 (23.9) | 32 (29.4) | 0.393 |
| Cerebrovascular disease | 6 (9.5) | 2 (4.3) | 8 (7.3) | 0.515 |
| Cognitive disorder | 0 | 1 (2.2) | 1 (0.9) | 0.874 |
| COPD | 2 (3.2) | 1 (2.2) | 3 (2.8) | 1.000 |
| Indication for ICU admission | ||||
| Respiratory failure | 37 (58.7) | 36 (78.3) | 73 (67.0) | 0.053 |
| Renal failure | 14 (22.2) | 5 (10.9) | 19 (17.4) | 0.198 |
| Cardiogenic cause | 15 (23.8) | 3 (6.5) | 18 (16.5) | 0.032 |
| Sepsis | 9 (14.3) | 9 (19.6) | 18 (16.5) | 0.637 |
| Others | 10 (15.9) | 5 (10.9) | 15 (13.8) | 0.640 |
| Medication | ||||
| Immunosuppressant | 17 (27.0) | 16 (34.8) | 33 (30.3) | 0.507 |
| Antipsychotics | 2 (3.2) | 6 (13.0) | 8 (7.3) | 0.114 |
| Benzodiazepines | 9 (14.3) | 3 (6.5) | 12 (11.0) | 0.332 |
| Benzodiazepine dose (equipotent lorazepam dose, mg/kg/day) | 0.0 (0.0–0.1) | 0.0 (0.0–0.4) | 0.0 (0.0–0.1) | 0.600 |
| Hypnotics | 3 (4.8) | 3 (6.5) | 6 (5.5) | 1.000 |
| Opioids | 10 (15.9) | 6 (13.0) | 16 (14.7) | 0.890 |
| Score | ||||
| APACHE II | 21.0 (16.0–27.0) | 18.5 (15.0–26.0) | 20.0 (15.0–26.0) | 0.215 |
| SOFA | 9.0 (7.0–12.0) | 8.0 (6.0–12.0) | 9.0 (6.0–12.0) | 0.190 |
| SAPS II | 45.0 (36.5–65.0) | 41.5 (28.0–49.0) | 44.0 (32.0–55.0) | 0.016 |
| Renal replacement therapy | 30 (47.6) | 12 (26.1) | 42 (38.5) | 0.037 |
Values are presented as median (interquartile range) or number (%).
Mg: magnesium; BMI: body mass index; DM: diabetes mellitus; COPD: chronic obstructive pulmonary disease; ICU: intensive care unit; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; SAPS: Simplified Acute Physiology Score.