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. 2022 Aug 11;13(18):2592–2605. doi: 10.1111/1759-7714.14595

FIGURE 6.

FIGURE 6

Apatinib is more effective in esophageal squamous cell carcinoma (ESCC) cells with low fibulin‐4 expression. (a) Eca109 and KYSE30 cells treated with apatinib or left untreated were analyzed by flow cytometry. The percentage of PE‐ and/or 7‐AAD‐positive cells is included in the panels. (b) The results are expressed as the percentages (mean standard deviation [SD] of three repeated experiments) of apoptotic/necrotic cells. (c) Effects of apatinib‐induced apoptosis. The error bars indicate the means ± SD averaged from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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