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. 2022 Sep 1;14:978740. doi: 10.3389/fnagi.2022.978740

TABLE 2.

Unadjusted and adjusted analyses of neutrophil count (×109/L), leukocyte count (×109/L), NLR with mRS 0–2 at 90days.

Parameters Cell counts (109/L) in quartiles Unadjusted analysis
Model 1
Model 2
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Leukocyte <8.40 Reference <0.001 Reference 0.007 Reference 0.008
8.40–11.06 0.55(0.34–0.89) 0.015 0.51(0.26–0.97) 0.041 0.52(0.26–1.04) 0.064
11.06–13.66 0.34(0.20–0.57) <0.001 0.42(0.21–0.82) 0.011 0.38(0.19–0.77) 0.007
>13.66 0.33(0.19–0.55) <0.001 0.32(0.16–0.64) 0.001 0.31(0.15–0.64) 0.002
Neutrophil <6.60 Reference <0.001 Reference 0.001 Reference 0.002
6.60–9.15 0.47(0.29–0.77) 0.002 0.43(0.22–0.83) 0.011 0.50(0.25–0.99) 0.047
9.15–11.96 0.38(0.23–0.63) <0.001 0.53(0.27–1.01) 0.055 0.48(0.24–0.96) 0.038
>11.96 0.27(0.16–0.46) <0.001 0.23(0.11–0.47) <0.001 0.22(0.11–0.48) <0.001
NLR <4.96 Reference <0.001 Reference 0.001 Reference 0.001
4.96–7.93 0.58(0.36–0.95) 0.030 0.46(0.24–0.87) 0.018 0.46(0.23—-0.91) 0.027
7.93–12.63 0.45(0.27–0.74) 0.002 0.45(0.23–0.89) 0.021 0.41(0.20–0.84) 0.016
>12.63 0.32(0.19–0.55) <0.001 0.22(0.11–0.44) <0.001 0.21(0.10–0.46) <0.001
Leukocyte, 109/L 0.89(0.84–0.93) <0.001 0.88(0.83–0.94) <0.001 0.88(0.82–0.95) <0.001
Neutrophil, 109/L 0.88(0.83–0.93) <0.001 0.87(0.81–0.93) <0.001 0.87(0.81–0.93) <0.001
NLR 0.95(0.92–0.98) 0.001 0.94(0.91–0.98) 0.001 0.94(0.91–0.98) 0.001

Model 1 adjusted for age, sex, hypertension, diabetes mellitus, baseline NIHSS score, baseline pc-ASPECTS, PC-CS score, stroke etiology, occlusion sites and pass.

Model 2 excluded patients without successful recanalization and adjusted for confounding factors in model 1.

OR, odds ratio; NLR, neutrophil-to-lymphocyte ratio; mRS, modified Rankin Scale.