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. 2022 Sep 1;14:978740. doi: 10.3389/fnagi.2022.978740

TABLE 4.

Unadjusted and adjusted analyses of neutrophil count (×109/L), leukocyte count (×109/L), NLR with mortality at 90 days.

Parameters Cell counts (109/L) in quartiles Unadjusted analysis
Model 1
Model 2
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Leukocyte <8.40 Reference 0.003 Reference 0.032 Reference 0.054
8.40–11.06 1.42(0.88–2.27) 0.150 1.32(0.74–2.34) 0.352 1.31(0.69–2.50) 0.410
11.06–13.66 1.65(1.03–2.64) 0.039 1.20(0.67–2.16) 0.536 1.29(0.67–2.46) 0.444
>13.66 2.42(1.51–3.88) <0.001 2.30(1.28–4.13) 0.005 2.40(1.25–4.62) 0.009
Neutrophil <6.60 Reference 0.001 Reference 0.006 Reference 0.008
6.60–9.15 1.68(1.05–2.70) 0.032 1.32(0.74–2.37) 0.352 1.24(0.65–2.39) 0.512
9.15–11.96 1.61(1.001–2.59) 0.050 1.08(0.60–1.95) 0.786 1.13(0.59–2.18) 0.709
>11.96 2.64(1.64–4.25) <0.001 2.55(1.41–4.60) 0.002 2.75(1.42–5.32) 0.003
NLR <4.96 Reference 0.005 Reference 0.027 Reference 0.017
4.96–7.93 1.56(0.97–2.50) 0.068 1.66(0.92–3.00) 0.093 1.73(0.88–3.40) 0.115
7.93–12.63 1.99(1.24–3.19) 0.005 1.82(1.004–3.32) 0.049 1.96(0.99–3.89) 0.053
>12.63 2.22(1.38–3.56) 0.001 2.50(1.38–4.55) 0.003 2.98(1.51–5.88) 0.002
Leukocyte, 109/L 1.08(1.03–1.13) <0.001 1.08(1.02–1.14) 0.004 1.09(1.03–1.15) 0.005
Neutrophil, 109/L 1.08(1.04–1.13) <0.001 1.09(1.03–1.15) 0.002 1.10(1.04–1.17) 0.002
NLR 1.02(1.00–1.04) 0.085 1.02(1.00–1.05) 0.046 1.02(0.996–1.05) 0.098

Model 1 adjusted for age, sex, hypertension, diabetes mellitus, baseline NIHSS score, baseline pc-ASPECTS, PC-CS score, stroke etiology, occlusion sites and pass.

Model 2 excluded patients without successful recanalization and adjusted for confounding factors in model 1.

OR, odds ratio; NLR, neutrophil-to-lymphocyte ratio; mRS, modified Rankin Scale.