TABLE 1.

Comparison of hydrophobicity scales that will be used in the present work.

Scale	Resolution	Principle	Notes	References
Bandyopadhyay-Methler	Residue	Local environment, Rekker coefficients (Rekker and Kort, 1979)		Bandyopadhyay and Mehler (2008)
Black-Mould	Residue	Rekker coefficients (Rekker and Kort, 1979)		Black and Mould (1991)
Eisenberg	Residue	Consensus of 5 previous scales		Eisenberg et al. (1982)
Jain	Residue	HIC retention		Jain et al. (2017a)
Kyte-Doolittle	Residue	Consensus of ΔG (water—vapor) and surface accessibility		Kyte and Doolittle (1982)
Meek	Residue	RP-HPLC retention	At pH 7.4	Meek (1980)
Miyazawa	Residue	Surface accessibility		Miyazawa and Jernigan (1985)
Rose	Residue	Fraction of surface area buried while folding		Eisenberg et al. (1982), Rose et al. (1985)
Wimley-White	Residue	ΔG (water—lipid bilayer)	Interface Scale	Wimley and White (1996)
Crippen	Atomic	LogP of small molecules		Wildman and Crippen (1999)
Eisenberg-dG	Atomic	Surface accessibility		Eisenberg and Mclachlan (1986)