Table 2. Minimum Inhibitory Concentrations (MICs) of 62 Isolates to the 6 Antifungals Tested.
| Species | MIC, μg/mL | |||||
|---|---|---|---|---|---|---|
| Fluconazole | Ketoconazole | Voriconazole | Terbinafine | Luliconazole | Itraconazole | |
| Trichophyton mentagrophytes (n = 34)a | ||||||
| Range | 0.125-32 | 0.25-4 | 0.0625-0.25 | 0.25-8 | 0.0625 | 0.125-0.5 |
| GM MIC | 1.37 | 1.2 | 0.073 | 1.303 | 0.0625 | 0.235 |
| MIC 50 | 4 | 1 | 0.0625 | 1 | 0.0625 | 0.125 |
| MIC 90 | 8 | 2 | 0.125 | 8 | 0.0625 | 0.5 |
| Trichophyton interdigitale (n = 13)b | ||||||
| Range | 1-8 | 0.5-4 | 0.0625-1 | 0.25-8.25 | 0.0625-0.5 | 0.125-1 |
| GM | 3.792 | 1.798 | 0.125 | 1.057 | 0.073 | 0.278 |
| MIC 50 | 4 | 2 | 0.125 | 1 | 0.0625 | 0.5 |
| MIC 90 | 8 | 4 | 0.25 | 8 | 0.0625 | 0.5 |
| Nannizzia gypsea (n = 6) a , c | ||||||
| Range | 0.5-4 | 0.0625-0.125 | 0.0625-0.125 | 0.0625-0.25 | 0.0625 | 0.125 |
| GM | 1.122 | 0.088 | 0.0702 | 0.079 | 0.0625 | 0.125 |
| MIC 50 | 0.5 | 0.0625 | 0.0625 | 0.0625 | 0.0625 | 0.125 |
| MIC 90 | 4 | 0.125 | 0.125 | 0.25 | 0.0625 | 0.125 |
| Trichophyton rubrum (n = 5)a | ||||||
| Range | 0.5-2 | 2-4 | 0.5 | 0.25-4 | 0.0625 | 0.125-1 |
| GM | 1.741 | 2.639 | 0.5 | 1 | 0.0625 | 0.435 |
| MIC 50 | 2 | 2 | 0.5 | 0.5 | 0.0625 | 0.5 |
| MIC 90 | 4 | 4 | 0.5 | 4 | 0.0625 | 1 |
| Trichophyton tonsurans (n = 2)a | ||||||
| Range | 1 | 4-8 | 0.0625-0.25 | 0.25-1 | 0.0625 | 0.125 |
| GM | 1 | 5.657 | 0.125 | 0.5 | 0.0625 | 0.125 |
| MIC 50 | 1 | 4 | 0.0625 | 0.25 | 0.0625 | 0.125 |
| MIC 90 | 1 | 8 | 0.25 | 1 | 0.0625 | 0.125 |
| Epidermophyton (n = 2)a | ||||||
| Range | 4 | 0.0625-0.125 | 0.0625-0.125 | 0.0625 | 0.0625 | 0.125 |
| GM | 4 | 0.088 | 0.088 | 0.0625 | 0.0625 | 0.125 |
| MIC 50 | 4 | 0.0625 | 0.0625 | 0.0625 | 0.0625 | 0.125 |
| MIC 90 | 4 | 0.125 | 0.125 | 0.0625 | 0.0625 | 0.125 |
Abbreviation: GM, geometric mean.
a
Culture-based identification.
b
Internal transcribed spacer sequencing–based identification.
c
Formerly known as Microsporum gypseum.