(A, D, and G)
Monocle 2 lineage trajectory model and associated Pseudotime predictions (B, E, and H) for skin samples indicated with proliferative and infundibulum clusters excluded. (G) is human scalp from (Cheng
et al,
2018). Pseudotime places the “Diff” basal cluster branch as most differentiated, as expected based on marker expression. (C, F, and I) Cartoons depicting two differentiation paths that based on LRC/non‐LRC marker expression can be defined as tail scale vs. interscales (F) and human rete ridges inter‐ridges (I); note mixed expressions along the two paths for back skin (C).
