Skip to main content
. 2022 May 10;14(5):mjac031. doi: 10.1093/jmcb/mjac031

Figure 3.

Figure 3

Diversified functions of cGAS. In addition to the canonical function as a cytosolic DNA sensor in the modulation of innate immunity, multifaceted roles of cGAS have been revealed. Importantly, cGAS is critical in regulating various biological processes including DNA damage repair, DNA replication, chromosome fusion, and micronucleophagy in a STING-independent manner (highlighted as light yellow background).