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. 2022 Sep 14;7(1):e001078. doi: 10.1136/bmjophth-2022-001078

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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(A) Intraocular pressure (IOP) of the four study groups. There was no difference in IOP levels between non glaucoma mice (SV-129) with or without (sham operated) bicommon carotid artery occlusion (BCCAO). There was no significant difference in IOP between DBA/2J mice with and without BCCAO as well. The graph shows the situation at 14 months of life. ** indicates p<0.001. (B) optokinetic head response at 0.066 cycle per degree as frequency of extinction (FE) (cycle/second). FE was significantly reduced in experimental animals 8 weeks after BCCAO at a spatial frequency of 0.066 cycle/degree. ** indicates p < 0.01, *** indicates p < 0.001.