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. 2022 Sep 14;9(2):e002039. doi: 10.1136/openhrt-2022-002039

Table 2.

Demographics and comorbidities of incident valve disease

No valve disease
(N=472 328)
Any valve disease
(N=13 615)
Mitral valve prolapse
(N=1119)
Mitral regurgitation
(N=6900)
Mitral stenosis
(N=2095)
Aortic regurgitation
(N=4238)
Aortic stenosis
(N=6020)
Tricuspid regurgitation
(N=1664)
Female, n (%) 259 071 (55) 5980 (44) 497 (44) 3242 (47) 1107 (3) 1829 (43) 2443 (41) 822 (49)
BMI >30 kg/m2, n (%) 114 072 (24) 4418 (33) 144 (13) 1969 (27) 557 (27) 1320 (31) 2228 (37) 561 (34)
SBP (mmHg) 140±20 145±21 141±20 144±21 143±21 145±21 147±21 144±21
Smoking (%) 6722 (1) 513 (4) 26 (2) 207 (3) 15 (1) 94 (2) 205 (3) 86 (5)
Dyslipidaemia, n(%) 9958 (2) 1855 (14) 105 (9) 794 (11.5) 47 (2.2) 360 (8.5) 776 (12.9) 222 (13.3)
Diabetes, n (%) 9564 (2.0) 1527 (11.2) 37 (3.3) 590 (8.6) 40 (1.9) 225 (5.3) 735 (12.2) 229 (13.8)
CAD, n (%) 4491 (1.0) 2069 (15.2) 119 (10.6) 911 (13.2) 51 (2.4) 417 (9.8) 883 (14.7) 202 (12.1)
CHF, n (%) 1545 (0.3) 1801 (13.2) 68 (6.1) 1098 (15.9) 99 (4.7) 254 (6.0) 430 (7.1) 395 (23.7)
Rheumatic fever, n(%) 30 (0.0) 891 (6.5) 32 (2.9) 836 (12.1) 927 (44.3) 146 (3.5) 130 (2.2) 214 (12.9)
Infective endocarditis, n (%) 105 (0.0) 974 (7.2) 52 (4.7) 902 (13.1) 932 (44.5) 155 (3.7) 125 (2.1) 225 (13.5)
Atrial fibrillation and flutter, n (%) 3965 (0.8) 3840 (28.2) 271 (24.2) 2867 (41.6) 1022 (48.8) 1694 (40.0) 2002 (33.3) 540 (32.5)
Pulmonary hypertension, n(%) 54 (0.0) 320 (2.4) 38 (3.4) 147 (2.1) 35 (1.7) 34 (0.8) 48 (0.8) 185 (11.1)

Values are expressed as mean±SD or n (%).

BMI, body mass index; CAD, coronary artery disease; CHF, congestive heart failure; SBP, systolic blood pressure.