Table 2.
Characteristics | Coefficient (95% CI) | P value |
CKD stages | ||
eGFR ≥90 | Reference | |
eGFR 60–89 | 3.9 (2.2 to 5.6) | <0.001 |
eGFR 30–59 | 3.0 (1.1 to 5.0) | 0.002 |
eGFR 15–29 | −0.9 (−4.0 to 2.2) | 0.58 |
eGFR <15/dialysis | −5.5 (−11.0 to 0.1) | 0.05 |
Age (/10 years) | 0.4 (−0.1 to 1.0) | 0.12 |
Sex, female | −0.7 (−1.6 to 0.2) | 0.14 |
Hypertension | 0.2 (−0.8 to 1.1) | 0.70 |
Diabetes mellitus | −2.1 (−3.4 to −0.9) | <0.001 |
Prior stroke/TIA/systemic embolism | 0.6 (−0.7 to 1.9) | 0.34 |
Prior MI | 0.7 (−1.3 to 2.6) | 0.50 |
Prior PCI or CABG | 0.2 (−1.5 to 1.9) | 0.82 |
Heart failure | −3.5 (−4.9 to −2.2) | <0.001 |
Peripheral vascular disease | −1.8 (−3.9 to 0.3) | 0.10 |
COPD | −6.3 (−8.2 to −4.5) | <0.001 |
Cancer (within 3 years) | −0.2 (−2.1 to 1.8) | 0.86 |
Prior major bleeding | −1.6 (−3.4 to 0.2) | 0.08 |
Acetylsalicylic acid | −1.5 (−2.6 to −0.4) | 0.01 |
P2Y12 inhibitor | 0.5 (−2.5 to 3.5) | 0.74 |
CABG, coronary artery bypass grafting; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; PCI, percutaneous coronary intervention; TIA, transient ischaemic attack; TTR, time in therapeutic range.