Table 6. IC50 (μM) Profile of Active Compounds.
test compound | non-small
cell Lung cancer |
breast cancer | colon cancer | ovarian cancer | HEK-293 | |
---|---|---|---|---|---|---|
A549 | NCI-H460 | MCF-7 | HCT-116 | SKOV-3 | ||
14g | nt | 6.65 | nt | 8.90 | 10.63 | nt |
14j | nt | 5.55 | nt | 10.45 | 32.50 | nt |
18b | 10.554 | nt | nt | nt | nt | nt |
18c | 3.69 | nt | nt | nt | nt | nt |
18f | 2.91 | nt | nt | nt | nt | 696 |
18m | 8.44 | nt | 9.35 | nt | nt | nt |
capsaicin | nt | 30.66 | nt | 40.16 | 22.03 | nt |
paclitaxel | 0.03 nM | nt | nt | nt | nt | nt |
doxorubicin | nt | 4.29 | 0.18 nM | 57.77 | 25.83 | nt |