. 2022 Aug 30;7(36):32131–32152. doi: 10.1021/acsomega.2c03368

Table 4. Permeability (P_e) of Commercial Drugs and 1c in the PAMPA-BBB Assay.

commercial drugs	lit.^a	exp.^b	cpd	P_e(10^–6 cm/s)	prediction
enoxacin	0.9	0.8	1c	8	CNS+
ofloxacin	0.8	0.8
verapamil	16	12
hydrocortisone	2	2
caffeine	1	3
progesterone	9	7
testosterone	17	12
piroxicam	2	2
atenolol	0.8	1
clonidine	5	4

Taken from refs (25) and (26).

Data are the mean of the two independent experiments.

Table 4. Permeability (Pe) of Commercial Drugs and 1c in the PAMPA-BBB Assay.