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. 2022 Sep 14;10:137. doi: 10.1186/s40478-022-01442-4

Fig. 1.

Fig. 1

Cohort characteristics. Based on H3K27me3 immunohistochemistry, 116 cases were classified as EPN_PFA showing a loss of immunoexpression, and 31 were EPN_PFB with a conserved H3K27me3 expression. From the 116 EPN_PFA, 108 were immunopositive for EZHIP and eight cases were immunopositive for the H3K27M mutation. From the national French Neuropathological Reference network (RENOCLIP-LOC) database, we found one additional pediatric case of EPN_PFA with H3K27M immunopositivity. Scale bars represent 50 µm