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. 2022 Sep 14;10:137. doi: 10.1186/s40478-022-01442-4

Fig. 3.

Fig. 3

Radiological and histopathological features of case #8. Axial T2-weighted image showing a circumscribed hemorrhagic lesion of the right cerebellopontine angle (a), with a low signal on T1-weighted images (b), and a peripheral enhancement on T1-weighted image with gadolinium injection (c). Ependymal features with pseudorosettes (d HPS, magnification 400×), associated with no immunoreactivity for Olig2 (e magnification 400×). Neurofilament immunostaining confirming the solid pattern (f magnification 400×). Immunoexpression of H3K27M in all tumor cells (g magnification 400×). Scale bars represent 50 µm. HPS: Hematoxylin Phloxin Saffron