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. 2022 Sep 15;22:284. doi: 10.1186/s12935-022-02706-8

Fig. 2.

Fig. 2

Constituent proteins of mTORC1 and mTORC2. A a central signaling molecule that is the mammalian target of rapamycin (mTOR) serves as a core constituent to form a distinctive complex with other molecules DEPTOR, PRAS40, mLST8 and Raptor, resulting in the formation of the mTORC1 complex, while the B mTOR with other five proteins DEPTOR, mSin1, Mlst8, Rictor and Protor forms the mTORC2 complex. Both the distinct protein complexes regulate several cellular mechanisms