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. 2022 Sep 1;13:867354. doi: 10.3389/fgene.2022.867354

TABLE 3.

Selected models proposed to address NBS expansion*.

Type of Model Description References
Decision analytic model A framework for compiling clinical and economic evidence in a systematic fashion, determining your product’s value, and communicating that value to decision makers. Grosse et al. (2016); Prosser et al. (2013), Prosser et al. (2018) www.treeage.com
Markov Model A mathematical model using the probabilities of different health states and the rates of transitions among them to recognize patterns, make predictions and to apply the statistics of sequential data. Chan et al. (2011) www.treeage.com
Discrete Event Simulation Model A method of simulating the behavior and performance of a real-life process, facility, or system. Salleh et al. (2017) www.mathworks.com
Microsimulation model A method of using individual-based state-transition models to reflect individual clinical pathways, incorporate the impact of history on future events, and capture the variation in patients’ characteristics at baseline. Verkleij et al. (2021) www.treeage.com
Agent-based model A computational model for simulating the actions and interactions of autonomous agents in order to understand the behavior of a system and what governs its outcomes. Tracy et al. (2018) www.anylogic.com
System dynamic models A computer-aided approach for strategy and policy design, which can portray processes of accumulation and feedback and that may be tested systematically to find effective policies for overcoming policy resistance. Yu et al. (2019) https://systemdynamics.org
System thinking models A way of approaching problems that asks how various elements within a system, (which could be an ecosystem, an organization, or something more dispersed such as a supply chain) can influence one another. Carey et al. (2015) www.vensim.com
*

Table 3 highlights the different models that can be used to conduct the different analyses indicated in Table 2. The availability of models is not limited to the list depicted here.