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PD-1 Reaction in Leiomyosarcoma. H&E stain of a case with primary leiomyosarcoma (case# 28, Additional Table 1) showing large malignant cells and scattered small lymphoid cells in the background. The corresponding PD-1 stain shows a positive staining of some of the lymphoid cells while the tumor as well as the remaining lymphoid cells are negative (40 × objective). Abbreviations: H&E, hematoxylin & eosin; PD-1, programmed cell death protein 1
