Table 2.

Subchondral structural parameters in the femoral condyle and tibia plateau

	Normal (n = 32)	Mild OA (n = 27)	Advanced OA (n = 29)
Lateral femoral condyle
BV/TV	0.269 ± 0.005	0.269 ± 0.005	0.273 ± 0.006 a b
Tb.Th	0.166 ± 0.004	0.166 ± 0.004	0.168 ± 0.004
Tb.Sp	0.452 ± 0.008	0.452 ± 0.008	0.448 ± 0.013
Tb.N	1.615 ± 0.031	1.615 ± 0.030	1.621 ± 0.040
Medial femoral condyle
BV/TV	0.269 ± 0.006	0.269 ± 0.005	0.273 ± 0.005 a b
Tb.Th	0.162 ± 0.004	0.163 ± 0.004	0.164 ± 0.003
Tb.Sp	0.442 ± 0.010	0.444 ± 0.010	0.437 ± 0.009 a b
Tb.N	1.652 ± 0.032	1.644 ± 0.034	1.662 ± 0.029
Lateral tibia plateau
BV/TV	0.266 ± 0.006	0.267 ± 0.005	0.268 ± 0.006
Tb.Th	0.162 ± 0.004	0.164 ± 0.006	0.166 ± 0.005 b
Tb.Sp	0.449 ± 0.009	0.451 ± 0.011	0.452 ± 0.009
Tb.N	1.633 ± 0.029	1.625 ± 0.042	1.617 ± 0.033
Medial tibia plateau
BV/TV	0.264 ± 0.006	0.264 ± 0.005	0.269 ± 0.005 a b
Tb.Th	0.159 ± 0.004	0.159 ± 0.004	0.163 ± 0.004 a b
Tb.Sp	0.443 ± 0.011	0.442 ± 0.009	0.442 ± 0.008
Tb.N	1.660 ± 0.035	1.664 ± 0.035	1.651 ± 0.027

Data are mean ± standard deviation. The significance between groups is shown based on ANCOVA with adjustment for age

^a P < 0.05 in comparison with control subjects

^b P < 0.05 in comparison between mild OA and advanced OA