Table 1.
Subject group characteristics—control (CTRL), diagnosed (Dx), and symptomatic (Sx)
| CTRL | Dx | Sx | Total | P value (CTRL vs Dx) | |
|---|---|---|---|---|---|
| Age (years) (mean ± SD) | 33.4 ± 5.4 | 35.2 ± 4.4 | 32.3 ± 8.2 | 33.6 ± 6.3 | 0.42 |
| BMI (kg/m2) (mean ± SD) | 24.2 ± 7.1 | 28.4 ± 5.4 | 26.8 ± 7.6 | 26.5 ± 6.8 | 0.15 |
| Age at menarche (years) (mean ± SD) | 12.0 ± 0.9 | 11.6 ± 1.6 | 12.6 ± 1.7 | 12.0 ± 1.5 | 0.51 |
| Race/ethnicity | 0.34 | ||||
| Caucasian | 7/9 (78%) | 0/11 (91%) | 13/13 (100%) | 30/33 (91%) | |
| Black | 1/9 (11%) | 0/11 (0%) | 0/13 (0%) | 1/33 (3%) | |
| Mixed | 1/9 (11%) | 0/11 (0%) | 0/13 (0%) | 1/33 (3%) | |
| Other | 0/9 (0%) | 1/11 (9%) | 0/13 (0%) | 1/33 (3%) | |
| Hispanic | 0/9 (0%) | 0/11 (0%) | 1/13 (8%) | ||
| Typical cycle length (days) | 0.52 | ||||
| 21–25 days | 0/9 (0%) | 1/11 (9%) | 3/13 (23%) | 4/33 (12%) | |
| 26–31 days | 8/9 (89%) | 7/11 (64%) | 8/13 (62%) | 23/33 (70%) | |
| 32–39 days | 1/9 (11%) | 2/11 (18%) | 2/13 (15%) | 5/33 (15%) | |
| > 40 days | 0/9 (0%) | 1/11 (9%) | 0/13 (0%) | 1/33 (3%) | |
| Typical bleed time (days) | 0.36 | ||||
| < 3 days | 0/9 (0%) | 2/11 (18%) | 0/13 (0%) | 2/33 (6%) | |
| 3–5 days | 5/9 (56%) | 6/11 (55%) | 8/13 (62%) | 19/33 (58%) | |
| 6–8 days | 4/9 (44%) | 3/11 (23%) | 5/13 (38%) | 12/33 (36%) | |
| Typical flow | 0.96 | ||||
| Light | 1/9 (11%) | 1/11 (9%) | 0/13 (0%) | 2/33 (6%) | |
| Moderate | 2/9 (22%) | 2/11 (18%) | 3/13 (23%) | 7/33 (21%) | |
| Moderately heavy | 3/9 (33%) | 5/11 (45%) | 9/13 (69%) | 17/33 (52%) | |
| Heavy | 3/9 (33%) | 3/11 (23%) | 1/13 (8%) | 7/33 (21%) | |
| Hormone use | 0.35 | ||||
| Yes | 0/9 (0%) | 1/11 (9%)+ | 1/13 (8%) | 2/33 (6%) | |
| Pain in this cycle | 0.06 | ||||
| Yes | 5/9 (56%) | 10/11 (91%) | 13/13 (100%)* | 28/33 (85%) | |
| None | 4/9 (44%) | 1/11 (9%) | 0/13 (0%) | 5/33 (15%) | |
| Mild | 2/9 (22%) | 3/11 (23%) | 3/13 (23%) | 8/33 (24%) | |
| Moderate | 3/9 (33%) | 6/11 (55%) | 4/13 (31%) | 13/33 (40%) | |
| Severe | 0/9 (0%) | 1/11 (9%) | 6/13 (46%) | 7/33 (21%) | |
| Pain medication in this cycle (Midol, Advil, Tylenol, Naproxen, Hydromorphone 2 mg/Baclofen/diazepam/Ketamine 8/10/15 mg) | |||||
| Yes | 1/9 (11%) | 6/11 (55%) | 10/13 (77%) | 17/33 (52%) | |
No comparisons of CTRL vs. Sx were significant for the above characteristics, except pain (yes/no): *p = 0.008; +one patient used 200mg of progesterone (Prometrium vaginal suppositories) 2 days prior to menses