Power based on three-arm design | ||
---|---|---|
Key Assumptions | 13 clusters per arm (alpha=0.05/2=0.025); m = 79; ICC = 0.012; CV = 0.47 |
|
Primary Outcome Comparison | Expected Effect Size | Power |
Combined Interventions (PD+CD) vs. Control Arm |
30% (PD+CD) – 8% (Control) = 22 percentage points |
99.8% |
Combined Interventions (PD+CD) vs. Client Directed Intervention (CD) |
30% (PD+CD) – 14.6% (CD) = 15.4 percentage points |
86.0% |
Notes: m, expected median cluster size by the end of the study; ICC, intraclass correlation coefficient; CV, coefficient of variation of cluster size