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. 2022 Sep 1;14:880576. doi: 10.3389/fnagi.2022.880576

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Copyright © 2022 Zheng, Liu, Zhang, Hu, Shang, Zhu, Huang, Wu, Xiao, Du, Liang, Chen, Zang, Hu, He, Zhang and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Conjunctional Manhattan plots depict the chromosomal location of each tested shared genetic loci between AD and glaucoma. (A) Conjunctional Manhattan plot of chromosomal locations and –log₁₀(ccFDR) values for associated SNPs of AD and glaucoma discovery sample. (B) Conjunctional Manhattan plot of chromosomal locations and –log₁₀(ccFDR) values for associated SNPs of AD and glaucoma replication sample. The X-axis is the chromosomal locations of significant shared loci. The Y-axis is the calculated –log₁₀(ccFDR) of significant shared loci. Detailed information about chromosomal locations for all significant loci is shown in Table 1.