Table 1.
Effect of EECT on carrageenan-induced paw oedema in rats (mean ± SEM, n = 6).
| Treatments | Mean edema volume (mL) and inhibition (%) |
||||
|---|---|---|---|---|---|
| 1 h | 2 h | 3 h | 4 h | 5 h | |
| Carrageenan | 0.15 ± 0.003 | 0.17 ± 0.007 | 0.42 ± 0.02 | 0.46 ± 0.01 | 0.17 ± 0.013 |
| Diclofenac (20 mg/kg) | 0.11 ± 0.007** (26.66%) |
0.09 ± 0.003*** (47.05%) |
0.09 ± 0.02*** (77.57%) |
0.03 ± 0.008*** (93.47%) |
0.01 ± 0.002*** (94.11%) |
| EECT (200 mg/kg) | 0.14 ± 0.009 ns (6.66%) |
0.12 ± 0.003*** (29.41%) |
0.10 ± 0.009*** (76.19%) |
0.06 ± 0.009*** (86.95%) |
0.03 ± 0.009*** (82.35%) |
| EECT (400 mg/kg) | 0.12 ± 0.010 ns (20%) |
0.10 ± 0.009*** (41.17%) |
0.09 ± 0.0*** (77.57%) |
0.05 ± 0.009*** (89.13%) |
0.02 ± 0.004*** (88.23%) |
Statistical analysis was done by one-way analysis of variation (ANOVA) followed by Dunnett’s test. ***P < 0.001, **P < 0.01, *P < 0.05 and ns- non significant. Standard and test were compared with carrageenan group.