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. 2020 Dec 1;13(2):243–249. doi: 10.1016/j.chmed.2020.11.004

Table 3.

Effect of EECT on CFA induced arthritis paw diameter (mean ± SEM, n = 6).

Groups Increase in paw diameter / mm
Day 3 Day 5 Day 7 Day 14 Day 21
Normal 0.07 ± 0.009 0.093 ± 0.4 0.09 ± 0.0 0.12 ± 0.0 0.13 ± 0.0
Arthritic control 2.48 ± 0.208*** 4.09 ± 0.3*** 4.9 ± 0.4*** 5.6 ± 0.2*** 6.63 ± 0.4***
CFA + Diclofenac (10 mg/kg) 2.03 ± 0.2 ns 3.10 ± 0.2 ns 3.53 ± 0.5 ns 2.86 ± 0.3*** 2.91 ± 0.0***
CFA + EECT (200 mg/kg) 2.2 ± 0.3 ns 3.800 ± 0.3 ns 4.03 ± 0.6 ns 3.8 ± 0.3* 4.60 ± 0.4***
CFA + EECT (400 mg/kg) 2.43 ± 0.3 ns 3.60 ± 0.4 ns 3.93 ± 0.5 ns 3.16 ± 0.4*** 3.30 ± 0.2***

Statistical analysis was done by one-way analysis of variation (ANOVA) followed by Tukey’s multiple comparison test. *P < 0.05, **P < 0.01, ***P < 0.001 and ns- non significant. Arthritic control was compared with normal and the treated groups were compared with arthritic control.