Table 1.

Synergistic effect of drugs.

Groups	Doses (g/kg)	Animals		Tumor weight/g	(fa)1,2	(fb)1,2	Synergistic effects
		Day 0	Day 11
Control		8	8
Model		8	7	1.32 ± 0.22
CTX	0.05	8	7	0.36 ± 0.056		73.06
BXT	2.07	8	7	1.01 ± 0.18		23.45
HWKL-D	1.6875	8	8	0.69 ± 0.098		47.48
HWKL-Z	3.375	8	8	0.66 ± 0.10		50.11
HWKL-G	6.75	8	8	0.55 ± 0.092		58.45
CTX + BXXXT	0.05 + 2.07	8	7	0.48 ± 0.012	79.38	63.71	No
CTX + HWKL-D	0.05 + 1.6875	8	8	0.24 ± 0.045	85.85	81.48	No
CTX + HWKL-Z	0.05 + 3.375	8	8	0.23 ± 0.029	86.56	82.33	No
CTX + HWKL-G	0.05 + 6.75	8	8	0.14 ± 0.021	88.81	89.53	Yes

(f_b)_1,2 was the actual inhibitory rate of drug 1with drug 2.

Synergistic effect was considered to be existed if (f_b)1,2 was larger than (f_a)1,2.