Table 8.
Effect of TIGP on cytokines in NASH rats (mean ± SD, n = 10).
| Groups | Doses/(mg·kg−1) | TNF-α/(pg·mL−1) | IL-6/(pg·mL−1) | MCP-1/(pg·mL−1) | LEP/(pg·mL−1) |
|---|---|---|---|---|---|
| Normal | − | 354 ± 86 | 135 ± 24 | 190 ± 24 | 936 ± 297 |
| Model | − | 571 ± 120## | 161 ± 31# | 231 ± 44# | 1336 ± 302## |
| TIGP | 20 | 524 ± 108 | 148 ± 21 | 226 ± 53 | 1275 ± 299 |
| TIGP | 40 | 499 ± 100 | 139 ± 34 | 198 ± 39 | 1068 ± 361 |
| TIGP | 80 | 426 ± 67** | 139 ± 27 | 205 ± 37 | 1043 ± 229* |
| Silybin | 160 | 444 ± 119* | 153 ± 27 | 205 ± 31 | 1231 ± 240 |
#
P <0.05 and
##
P <0.01 vs corresponding normal control group.
⁎
P<0.05 and
⁎⁎
P < 0.01 vs corresponding model control group.