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. 2020 Mar 12;12(2):104–117. doi: 10.1016/j.chmed.2020.03.002

Table 2.

Examples of domestic resources of some imported drugs.

Physicochemical indexes Imported drugs Domestic resources Remarks
Styrax benzoin S. macrothtyrsus, S. subniveus, S. hypoglauca The clinical application proves that domestic benzoin has the same effect as imported one, and importing is stopped presently.
total balsamic acid (calculated by alcoholic extract) 26%−35% 25.17%−31.46%
Strychnos nux-vomica S. wallichiana S. wallichiana has been used for drug production. We have also analyzed many Chinese species of Strychnos.
total alkaloid 2%−5% 2.19%
strychnine 1%−1.4% 1.34%
Acacia senegal farnesiana, A. decurrens, A. decurrns var. mollis It is proved that most of the domestic gum can be used clinically.
viscosity of tree gum (centistoke) 1.4855 1.0881–1.7818
suspension force measurement (hr) 40 24–64
emulsifying properties qualified superior to or close to Arabic gum
appearance Picrorrhiza kurroa α(dark brown)-γ-(light gray, yellow and black) P. scrophulariae α(dark brown)-γ-(light gray, yellow and black) P. scrophulariae has been used for drug production
alcohol extract content 45.96% 44.21%;49.20%
water extract content 36.98% 35.05%;37.82%
bitter ratio 60 60
Hydrocarpus anthelmintica H. hainanensis According to the physicochemical properties and seed morphology, there is little difference between domestic and imported Hydrocarpus, which needs further clinical confirmation.
oil content shelled kernel 45.36% shelled kernel 44.96%
oil freezing point yellow oily liquid at room temperature white solid at room temperature
iodine value 84.74 76.29
specific gravity 0.809 0.928
refractive index (20 °C) 1.4786 1.4758
coloring reaction of gynocardia oil ①a few drops of oil+ one drop of trichloroacetic acid and 4 drops of HCl; slight heat and show blue color ① also blue
②a few drops of oil+5 drops of glacial acetic acid and HCl (9:1); heated slightly, dark blue ② dark blue
③1 ml oil+H2SO4; first red-brown, then olive-green ③ first red-brown, then olive-green
Ferula asafoetida F. sinkiangensis F. sinkiangensis has been used for drug production
alkali addition after grinding with water orange-yellow emulsion, yellowish-green emulsion with alkali white emulsion, yellow emulsion with alkali
alcohol extract with a few drops of phloroglucin and concentrated HCl pink, but a little deep pink
umbelliferone reaction blue fluorescence blue fluorescence
volatile oil content 6%−17% 17.5%−18.5%
sulfur content 17%−38% 20.6%
specific gravity (20 °C) 0.906–0.973 0.974
refractive index (20 °C) 1.493–1.518 1.529