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. 2021 Dec 21;14(1):104–110. doi: 10.1016/j.chmed.2021.09.013

Table 2.

Effects of N-FBRT and FBRT on serum fibrosis biomarkers and hepatic hydroxyproline content of rats with liver fibrosis (mean ± SD, n = 8).

Groups HA/(ng/mL) LN/(ng/mL) PC-III/(ng/mL) C-IV/(ng/mL) Hyp/(ng/g)
Control 78.35 ± 14.93 45.31 ± 2.98 23.00 ± 4.66 94.07 ± 12.23 36.06 ± 6.36
CCl4 183.00 ± 29.05** 75.67 ± 8.28** 51.00 ± 9.14** 256.16 ± 26.90** 132.54 ± 11.47**
N-FBRT1 108.75 ± 17.02## 52.04 ± 4.07## 31.25 ± 6.29## 123.95 ± 21.84## 39.40 ± 12.07##
N-FBRT2 123.00 ± 27.08# 45.95 ± 2.95## 38.00 ± 13.88 132.84 ± 22.71## 66.84 ± 26.04##
N-FBRT3 137.50 ± 28.79 55.56 ± 6.10# 40.85 ± 7.56 144.50 ± 10.69## 70.94 ± 15.60##
N-FBRT4 147.00 ± 17.39 61.59 ± 5.91 43.00 ± 8.6 143.92 ± 19.77## 97.30 ± 39.80
FBRT 113.35 ± 22.35## 47.60 ± 4.54## 34.85 ± 4.91# 122.87 ± 22.21## 66.87 ± 14.21##
Colchicine 107.50 ± 18.44## 44.59 ± 7.37## 32.15 ± 5.15## 115.37 ± 27.57## 47.93 ± 23.71##
**

P < 0.01 vs control group; #P < 0.05, ##P < 0.01 vs CCl4 model group.