. 2022 Aug 28;28(32):4649–4667. doi: 10.3748/wjg.v28.i32.4649

Table 6.

Univariate and multivariate analyses of prognostic factors associated with 5-year overall survival

Variables	N	Univariate		Multivariate
Variables	N	5-yr OS rate (%)	P value	HR (95%CI)	P value
Total	195
Sex
Male	128	87.9	0.3274
Female	67	85.3	0.3274
Age
< 65	77	89.7	0.4113
65	118	85.2	0.4113
Location
U	41	80.9	0.2629
M, L	154	88.6	0.2629
Tumor length (mm)
< 30	63	97.8	0.0020^a	3.010 (0.347-26.12)	0.3176
30	132	80.1	0.0020^a
Histological type
tub1, tub2, pap	96	88.3	0.4544
por, sig, muc	99	85.6	0.4544
Lymphatic invasion
Negative	110	96.1	0.0002^a	1.872 (0.549-6.384)	0.3166
Positive	85	75.7	0.0002^a
Venous invasion
Negative	131	90.6	0.0126^a	1.085 (0.476-2.472)	0.8469
Positive	64	79.3	0.0126^a
pT
pT1-2	137	95.9	< 0.0001^a	5.240 (1.807-15.20)	0.0023^c
pT3-4	58	65.5	< 0.0001^a
pN
pN0	139	94.1	< 0.0001^a	2.148 (0.695-6.643)	0.1844
pN1-3	56	67.6	< 0.0001^a
IHC score
< 1.3	137	89.6	0.0104^a	2.318 (1.016-5.288)	0.0457^c
1.3	58	73.9	0.0104^a

P < 0.05: Log-rank test.

P < 0.05: Cox hazard regression analysis.

CI: Confidence interval; HR: Hazard ratio; IHC: Immunohistochemical; L: Lower; M: Middle; muc: Mucinous adenocarcinoma; OS: Overall survival; pap: Papillary adenocarcinoma; pN: Pathological N stage; por: Poorly differentiated adenocarcinoma; pT: Pathological T stage; sig: Signet-ring cell carcinoma; tub: Tubular adenocarcinoma; U: Upper.