Table 4.
Haematological parameters in different treatment groups
|
No.
|
Group
|
Hb,g/L
|
Total RBC as 1012/L
|
PCV, L/L
|
MCV, fL
|
MCH, pg
|
MCHC, g/L
|
RDW, %
|
Total WBC as 109/L
|
N, %
|
L, %
|
M, %
|
E, %
|
B, %
|
Plts as 109/L
|
| 1 | Untreated | 121 ± 1.0 | 7.91 ± 0.9 | 0.36 ± 0.0 | 46 ± 1.5 | 15 ± 0.7 | 332 ± 1.1 | 20.6 ± 1.0 | 5.8 ± 1.3 | 37 ± 1.0 | 55 ± 1.1 | 5 ± 0.8 | 2 ± 0.1 | 1 ± 0.0 | 790 ± 1.2 |
| 2 | Gemcitabine (10 mg/kg per 3 d) | 118 ± 1.4 | 7.60 ± 1.1 | 0.38 ± 0.0 | 50.0 ± 1.8 | 16.0 ± 0.6 | 313 ± 1.8 | 22.1 ± 0.7 | 6.0 ± 1.2 | 33.0 ± 1.2 | 60.0 ± 0.7 | 6.0 ± 1.3 | 1.0 ± 0.1 | 0.0 ± 0.1 | 720 ± 1.4 |
| 3 | O.s (200 mg/kg per day) | 118 ± 1.5 | 8.0 ± 0.8 | 0.38 ± 0.0 | 48.0 ± 2.0 | 15.0 ± 1.1 | 307 ± 0.9 | 22.3 ± 1.6 | 6.10 ± 0.7 | 35.0 ± 0.8 | 53.0 ± 0.6 | 9.0 ± 1.0 | 1.0 ± 0.1 | 2.0 ± 0.0 | 801 ± 0.8 |
| 4 | O.s (200 mg/kg per day) and gemcitabine (10 mg/kg per 3 d) combination | 115 ± 1.7 | 7.1 ± 1.4 | 0.35 ± 0.0 | 50.0 ± 1.6 | 16.0 ± 0.7 | 321 ± 1.5 | 21.5 ± 0.8 | 5.70 ± 1.5 | 32.0 ± 0.9 | 60.0 ± 1.1 | 5.0 ± 0.7 | 2.0 ± 0.1 | 1.0 ± 0.1 | 760 ± 0.9 |
| 5 | O.s (400 mg/kg per day) | 123 ± 1.6 | 7.9 ± 0.7 | 0.36 ± 0.0 | 46.0 ± 1.5 | 16.0 ± 1.6 | 335 ± 2.0 | 21.0 ± 0.9 | 5.70 ± 1.8 | 33.0 ± 1.2 | 61.0 ± 1.2 | 4.0 ± 0.6 | 2.0 ± 0.1 | 0.0 ± 0.0 | 740 ± 1.0 |
| 6 | O.s (400 mg/kg per day) and gemcitabine (10 mg/kg per 3 d) combination | 123 ± 1.1 | 7.70 ± 0.9 | 0.36 ± 0.0 | 47.0 ± 1.2 | 16.0 ± 0.4 | 331 ± 1.2 | 22.6 ± 1.3 | 6.0 ± 1.5 | 30.0 ± 0.9 | 60.0 ± 1.1 | 8.0 ± 1.3 | 1.0 ± 0.1 | 1.0 ± 0.0 | 810 ± 1.3 |
Results are expressed as mean ± SD (n = 6). The P values in all treated groups were insignificant compared to the untreated group. No statistical difference was also observed among all treatment groups using two-way ANOVA and Tukey’s honest significant difference posthoc test. B: Basophile; E: Eosinophile; Hb: Haemoglobin; L: Lymphocyte; M: Monocyte; MCH: Mean cell haemoglobin; MCHC: Mean cell haemoglobin concentration; MCV: Mean cell volume; N: Neutrophile; O.s: Orthosiphon stamineus; PCV: Packed cell volume; Plts: Platelets; RBC: Red blood cells; RDW: Red cell distribution width; WBC: White blood cells.