The rate constant of the M6 reactants combine with different nucleophile groups to form target products.
| Species | Yield | Energy barrier (kcal mol−1) | k TS4 (s−1) |
|---|---|---|---|
| HN-2A | 90% | −4.6 | 1.6 × 10−6 |
| 2A-OH | 77% | 2.7 | 8.6 × 10−8 |
| N-2A | 19% | 2.6 | 9.0 × 10−8 |
| HO-2A | 6% | 2.6 | 9.0 × 10−8 |