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. 2022 Sep 15;4(3):lqac067. doi: 10.1093/nargab/lqac067

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© The Author(s) 2022. Published by Oxford University Press on behalf of NAR Genomics and Bioinformatics.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — UpSet plot of the intersection of upregulated (panel A) and downregulated (panel B) superfamilies in 19 cancer types. The dark bar plot on the left shows the number of upregulated and downregulated superfamilies for each type of cancer respectively. The dot-matrix represents the different intersections. In A, sky blue: intersections of superfamilies upregulated in 1 or 2 cancer types, dark blue: intersections of superfamilies upregulated in at least three cancer types and up to 12. In B, green: intersection of superfamilies downregulated in one or two cancer types, orange: intersection of superfamilies downregulated in at least three cancer types and up to 12, pink: superfamilies downregulated in 12 or more cancer types. In both panels A and B, the colored bar chart at the top represents the number of superfamilies that each intersection contains. KICH: Kidney Chromophobe, BLCA: Bladder Urothelial Carcinoma, LUSC: Lung squamous cell carcinoma, READ: Rectum adenocarcinoma, KIRC: Kidney renal papillary cell carcinoma, COAD: Colon adenocarcinoma, HNSC: Head and Neck squamous cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LUAD: Lung adenocarcinoma, LIHC: Liver hepatocellular carcinoma, UCEC: Uterine Corpus Endometrial Carcinoma, PRAD: Prostate adenocarcinoma, STAD: Stomach adenocarcinoma, ESCA: Esophageal carcinoma, BRCA: Breast invasive carcinoma, THCA: Thyroid carcinoma, WT: Wilms Tumor, RT: Rhabdoid Tumor, AML: Acute Myeloid Leukemia.