Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 11;15:5247–5263. doi: 10.2147/JIR.S377499

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Luo et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

RNA-seq analysis of DEGs after C/EBPβ inhibition. (A) Flow chart of sample preparation for RNA-seq. (B) Heat maps of differentially expressed genes (DEGs). (C) Volcano plot indicating substantial changes in gene expression between the LPS and CON groups (up) and (down). (D) Volcano plot indicating substantial changes in gene expression between the LPS + Lv-sh-C/EBPβ and LPS + Lv-sh-NC groups (up) and (down). (E) Validation of C/EBPβ-regulated DEGs in alveolar macrophages using RT-qPCR. **p < 0.01, and ***p < 0.001 compared with the CON group. ^###p < 0.001 compared with the LPS + sh-NC group.