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. 2022 Sep 11;16:3071–3085. doi: 10.2147/DDDT.S378786

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© 2022 Xie et al.

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Dihydromyricetin treatment alleviated cerebral I/R injury in rats. Rats were subjected to MCAO/R to induce cerebral I/R injury and then administered DHM treatment in increasing doses. Sham-operated rats served as controls. (A) The neurological scores of rats. (B) Brain water content of rats. (C) Infarct volume of brain tissues as assessed by TTC staining. (D) Apoptotic cells in brain tissues were examined by TUNEL staining. ^**P < 0.01, compared with the sham group. ^#P < 0.05, ^##P < 0.01, compared with the MCAO/R group.