Table 3.

Effect of Intervention vs Standard of Care on Trial Outcomes Among Household Contacts Who Were Present at Baseline List of Household Contacts

Outcome	Standard of Care	Household Intervention
Primary Outcome			Hazard Ratio (95% CI)
Contacts diagnosed with TB	31/2551 (1.2%)	51/3188 (1.6%)	1.33 (.83–2.16)
Contact deaths	49/3961 (1.2%)	42/4242 (1.0%)	0.72 (.47–1.10)
TB or death	80/2600 (3.1%)	93/3230 (2.9%)	0.90 (.66–1.24)
Secondary Outcomes			Odds Ratio (95% CI)
Prevalence of tuberculin skin test positivity (≥10 mm) among children aged ≤14 years	15/800 (1.9%)	38/845 (4.5%)	2.25 (1.07–4.72)
Prevalence of undiagnosed or untreated human immunodeficiency virus infection	32/2543 (1.3%)	41/3185 (1.3%)	1.02 (.64–1.64)

Hazard ratios and odds ratios were calculated with the standard of care arm as the reference group; intracluster correlation coefficients were TB (0.04), death (0.004), TB or death (0.02), tuberculin skin test positivity (0.86), and undiagnosed/untreated human immunodeficiency virus (0.08).

Abbreviations: CI, confidence interval; TB, tuberculosis.