Table 1.
Baseline Characteristics and Acquisition of Single-Nucleotide Polymorphisms Among Patients With Pulmonary Tuberculosis With Treatment Failure or Recurrence in India
| Characteristic | Overall (N = 76) | Treatment Failure (n = 40) | TB Recurrence (n = 36) |
|---|---|---|---|
| Sex | |||
| Female | 14 (18) | 10 (25) | 4 (11) |
| Male | 62 (82) | 30 (75) | 32 (89) |
| Age, y, median (IQR) | 38 (26–48) | 38 (26–48) | 38 (27–47) |
| BMI, kg/m2, median (IQR) | 16 (15–19) | 17 (15–19) | 16 (14–19) |
| HIV | 1 (1) | 1 (3) | 0 |
| Smoker | 29 (38) | 15 (38) | 14 (39) |
| Uses alcohol | 44 (58) | 21 (53) | 23 (64) |
| Hemoglobin, g/dL, median (IQR) | 12.0 (10.7–13.5) | 11.5 (10.4–13.3) | 12.5 (11.2–13.7) |
| HbA1c, %, median (IQR) | 5.9 (5.6–6.7) | 5.8 (5.6–6.3) | 6.0 (5.6–7.3) |
| Diabetes mellitus | |||
| Yes | 22 (29) | 10 (25) | 12 (33) |
| No | 54 (71) | 30 (75) | 24 (67) |
| SNP acquisition excluding exogenous reinfection | |||
| <1 SNP | 58 (92) | 32 (94) | 26 (90) |
| >2 SNP | 5 (8) | 2 (6) | 3 (10) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: BMI, body mass index; DM, diabetes mellitus; HbA1c, hemoglobin A1c; HIV, human immunodeficiency virus; IQR, interquartile range; SNP, single-nucleotide polymorphism; TB, tuberculosis.