Table 3.
Patient ID | Participant Origin | Outcome | SNP Difference, No. | Lineage | |
---|---|---|---|---|---|
Baseline | Outcome | ||||
TB-only | |||||
1 | Chennai | Recurrence | 522 | East Africa Indian Ocean | East Africa Indian Ocean |
2 | Chennai | Failure | 1092 | Beijing East Africa | European American |
3 | Pune | Recurrence | 186 | Delhi Central Asia | Delhi Central Asia |
4 | Pune | Failure | 267 | Delhi Central Asia | Delhi Central Asia |
5 | Pune | Failure | 1026 | European American | Delhi Central Asia |
6 | Pune | Recurrence | 1099 | Delhi Central Asia | European American |
7 | Pune | Failure | 24 | Unknown | Unknown |
8 | Pune | Failure | 155 | Delhi Central Asia | Delhi Central Asia |
9 | Pune | Failure | 1062 | European American | Delhi Central Asia |
TB-DM | |||||
10 | Chennai | Recurrence | 21 | East Africa Indian Ocean | East Africa Indian Ocean |
11 | Chennai | Recurrence | 21 | East Africa Indian Ocean | East Africa Indian Ocean |
12 | Chennai | Recurrence | 532 | East Africa Indian Ocean | East Africa Indian Ocean |
13 | Chennai | Failure | 503 | East Africa Indian Ocean | East Africa Indian Ocean |
Abbreviations: DM, diabetes mellitus; ID, identification; SNP, single-nucleotide polymorphism; TB, tuberculosis.
SNP difference >8 among paired Mycobacterium tuberculosis strains isolated at baseline and tuberculosis treatment outcome (treatment failure or recurrence).