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. 2022 Jan 4;75(5):768ā€“776. doi: 10.1093/cid/ciab1067

Table 3.

Differences in Single-Nucleotide Polymorphisms and Lineage Among Paired Mycobacterium tuberculosis Strains Isolated From Participants With Exogenous Tuberculosis Reinfectiona, According to Diabetes Mellitus Status (nā€…=ā€…13)

Patient ID Participant Origin Outcome SNP Difference, No. Lineage
Baseline Outcome
TB-only
1 Chennai Recurrence 522 East Africa Indian Ocean East Africa Indian Ocean
2 Chennai Failure 1092 Beijing East Africa European American
3 Pune Recurrence 186 Delhi Central Asia Delhi Central Asia
4 Pune Failure 267 Delhi Central Asia Delhi Central Asia
5 Pune Failure 1026 European American Delhi Central Asia
6 Pune Recurrence 1099 Delhi Central Asia European American
7 Pune Failure 24 Unknown Unknown
8 Pune Failure 155 Delhi Central Asia Delhi Central Asia
9 Pune Failure 1062 European American Delhi Central Asia
TB-DM
10 Chennai Recurrence 21 East Africa Indian Ocean East Africa Indian Ocean
11 Chennai Recurrence 21 East Africa Indian Ocean East Africa Indian Ocean
12 Chennai Recurrence 532 East Africa Indian Ocean East Africa Indian Ocean
13 Chennai Failure 503 East Africa Indian Ocean East Africa Indian Ocean

Abbreviations: DM, diabetes mellitus; ID, identification; SNP, single-nucleotide polymorphism; TB, tuberculosis.

SNP difference >8 among paired Mycobacterium tuberculosis strains isolated at baseline and tuberculosis treatment outcome (treatment failure or recurrence).