Table 3.
Changes in excised wound size after topical application of the 5% and 10% extract ointment of Verbascum sinaiticum on rats.
| Wound area (mm2) postwounding days | ||||||||
|---|---|---|---|---|---|---|---|---|
| Groups | 2 | 4 | 6 | 8 | 10 | 12 | 14 | 16 |
| BO | 295.0 ± 2.54 | 283.8 ± 2.81 | 260.0 ± 2.3 | 247.9 ± 29.8 | 188.6 ± 2.00 | 153.9 ± 3.55 | 122.1 ± 2.49 | 94.3 ± 3.52 |
| NFO (0.02%) | 271.3 ± 12.8a3 | 198.5 ± 5.3a2 | 167.6 ± 11a3 | 130.1 ± 17.7a3 | 104.2 ± 16.5a3 | 78.9 ± 18.5a3 | 57.8 ± 22.39a2 | 33.5 ± 22.8a3 |
| 5% extract ointment | 258.3 ± 3.5a3 | 220.0 ± 13.4a3 | 188.5 ± 13.3a2 | 144 ± 39.9a3 | 104.5 ± 11.05a3 | 81.89 ± 14.8a3 | 51.3 ± 18.25a3 | 23.9 ± 13.7a3 |
| 10% extract ointment | 261.2 ± 6a3 | 203.2 ± 3.6a3 | 162.7 ± 5.57 | 131.2 ± 12.5a3 | 118.1 ± 3.3a3 | 99.2 ± 8.52a3 | 62.1 ± 14.06a2 | 24.9 ± 10.6a3 |
Values are expressed as mean ± S.E.M (n = 6); all superscripts indicate significance. a compared to control group; 2 = p < 0.01, 3 = p < 0.001; numbers from 2 to 16 indicate the day on which contraction rate measurement was taken; BO = base ointment; NFO = nitrofurazone ointment.