Table 2.
Laboratory characteristics of the study participants.
| Lab parameter | Before or after receiving the capsule | Mean ± SD | P value | ||
|---|---|---|---|---|---|
| Placebo (n = 20) | OEA 300 mg/day (n = 20) | OEA 600 mg/day (n = 20) | |||
| Ur | Before | 43.16 ± 10.98 | 52.25 ± 12.65 | 41.8 ± 12.63 | 0.796 |
| After | 38.5 ± 12.34 | 42.25 ± 8.22 | 36.6 ± 14.04 | ||
| P value | 0.56 | 0.046 | 0.168 | ||
|
| |||||
| Cr | Before | 1.12 ± 0.32 | 1.34 ± 0.15 | 1.06 ± 0.17 | 0.466 |
| After | 1.05 ± 0.23 | 1.17 ± 0.24 | 0.98 ± 0.13 | ||
| P value | 0.353 | 0.030 | 0.210 | ||
|
| |||||
| TG | Before | 109.5 ± 37.22 | 116.12 ± 44.87 | 108 ± 60.81 | 0.964 |
| After | 77.75 ± 7.22 | 88.37 ± 27.72 | 74.5 ± 20.5 | ||
| P value | 0.126 | 0.044 | 0.449 | ||
|
| |||||
| Chl | Before | 149.5 ± 41.58 | 163.4 ± 37.62 | 156.5 ± 30.55 | 0.659 |
| After | 135.25 ± 47.61 | 136.8 ± 28.60 | 140.9 ± 30.96 | ||
| P value | 0.217 | 0.027 | 0.138 | ||
|
| |||||
| HDL | Before | 47.85 ± 28.32 | 33.25 ± 6.38 | 35 ± 3.69 | 0.317 |
| After | 47.42 ± 30.70 | 37.83 ± 5.89 | 39 ± 7.89 | ||
| P value | 0.834 | 0.035 | 0.288 | ||
|
| |||||
| ALT | Before | 16.71 ± 6.87 | 19.33 ± 4.50 | 15 ± 3.31 | 0.170 |
| After | 18.57 ± 7.67 | 18.22 ± 4.65 | 14.2 ± 1.92 | ||
| P value | 0.374 | 0.007 | 0.374 | ||
|
| |||||
| AST | Before | 13.5 ± 2.51 | 19.66 ± 2.65 | 19.57 ± 7.16 | 0.424 |
| After | 16 ± 8.28 | 19 ± 2.75 | 19.14 ± 6.98 | ||
| P value | 0.591 | 0.235 | 0.078 | ||
|
| |||||
| IL-6 | Before | 2.42 ± 1.32 | 3.24 ± 1.81 | 3.20 ± 1.57 | 0.035 |
| After | 3.18 ± 1.54 | 2.13 ± 0.59 | 3.26 ± 1.19 | ||
| P value | 0.216 | 0.040 | 0.888 | ||
|
| |||||
| CRP | Before | 4.25 ± 3.77 | 4.98 ± 3.16 | 4.17 ± 2.20 | 0.235 |
| After | 4.59 ± 4.12 | 3.04 ± 1.54 | 4.44 ± 1.28 | ||
| P value | 0.831 | 0.049 | 0.743 | ||
|
| |||||
| SOD | Before | 0.24 ± 0.011 | 0.251 ± 0.013 | 0.25 ± 0.01 | 0.369 |
| After | 0.25 ± 0.018 | 0.253 ± 0.023 | 0.24 ± 0.02 | ||
| P value | 0.187 | 0.792 | 0.435 | ||
|
| |||||
| TAC | Before | 0.59 ± 0.08 | 0.63 ± 0.082 | 0.70 ± 0.08 | 0.464 |
| After | 0.61 ± 0.12 | 0.71 ± 0.099 | 0.73 ± 0.14 | ||
| P value | 0.637 | 0.020 | 0.478 | ||
|
| |||||
| MDA | Before | 0.089 ± 0.011 | 0.106 ± 0.021 | 0.097 ± 0.026 | 0.054 |
| After | 0.090 ± 0.017 | 0.091 ± 0.018 | 0.080 ± 0.016 | ||
| P value | 0.820 | 0.026 | 0.007 | ||
|
| |||||
| TTG | Before | 0.140 ± 0.017 | 0.151 ± 0.016 | 0.155 ± 0.017 | 0.022 |
| After | 0.134 ± 0.025 | 0.167 ± 0.016 | 0.151 ± 0.017 | ||
| P value | 0.494 | 0.016 | 0.266 | ||
Abbreviations: Cr, Creatinine; Ur, Urea; Chl, Cholesterol; TG, Triglyceride; HDL, high-density lipoprotein; AST, aspartate transaminase; ALT, alanine transaminase; CRP, C-reactive protein; IL-6, interlukin-6; TAC, total antioxidant capacity; TTG, total thiol groups; MDA, malondialdehyde; SOD, superoxide dismutase.