Table 2.

Treatment-related death and all cause death rate during trials by cancer types

		Number of patients	Number of events	%	95%CI
Treatment-related death	All patients	13847	93	0.67	(0.54, 0.82)
	Bladder	257	1	0.39	(0.01, 2.15)
	Breast	1010	7	0.69	(0.28, 1.42)
	Colon	1438	11	0.76	(0.38, 1.36)
	Kidney	310	1	0.32	(0.01, 1.78)
	Lung	982	9	0.92	(0.42, 1.73)
	Melanoma	779	1	0.13	(0, 0.71)
	Ovary	1518	9	0.59	(0.27, 1.12)
	Pancreas	530	3	0.57	(0.12, 1.65)
	Prostate	288	3	1.04	(0.22, 3.01)
	Others	6735	48	0.71	(0.53, 0.94)
Death during trial*	All patients	13847	1111	8.02	(7.58, 8.49)
	Bladder	257	34	13.23	(9.34, 17.99)
	Breast	1010	84	8.32	(6.69, 10.19)
	Colon	1438	120	8.34	(6.97, 9.9)
	Kidney	310	13	4.19	(2.25, 7.06)
	Lung	982	78	7.94	(6.33, 9.81)
	Melanoma	779	59	7.57	(5.82, 9.66)
	Ovary	1518	43	2.83	(2.06, 3.8)
	Pancreas	530	79	14.91	(11.98, 18.23)
	Prostate	288	7	2.43	(0.98, 4.94)
	Others	6735	594	8.82	(8.15, 9.52)

^*Death during trial: all death regardless of attribution

Abbreviations: CI, confidence interval computed using the exact method