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. 2022 Aug 17;609(7927):597–604. doi: 10.1038/s41586-022-05084-3

Extended Data Fig. 6. Coarse-grained schematic suggested by growth laws.

Extended Data Fig. 6

Schematic of oocyte cortex formation through an intermediate stage with WSP-1, ARP2/3 complex, and F-actin condensates. The four processes that underly the dynamic instability of condensates are WSP-1 self-recruitment, branching-dependent WSP-1 loss, branching-dependent F-actin growth, and F-actin loss (depolymerization or severing modulated by ARP2/3). The effect of arx-2 RNAi on the F-actin loss coefficient is indicated. As the rate coefficients reflect the summed effect of all processes affecting composition dependent condensate growth molecular mechanisms are likely to be more involved, but maintain the depicted overall structure.